Diagnosis and surgical treatment of autoimmune pancreatitis
10.3760/cma.j.cn113855-20220906-00549
- VernacularTitle:自身免疫性胰腺炎的诊断与外科治疗
- Author:
Yuting HOU
1
;
Yongsu MA
;
Xiaochao GUO
;
Jixin ZHANG
;
Xiaodong TIAN
;
Yinmo YANG
Author Information
1. 北京大学第一医院外科，北京 100034
- Keywords:
Autoimmune diseases;
Pancreatitis;
Diagnosis;
Treatment
- From:
Chinese Journal of General Surgery
2023;38(5):326-329
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the indications and effect of surgical treatment of autoimmune pancreatitis.Methods:Clinical data of these 15 patients with autoimmune pancreatitis diagnosed and treated at the Department of General Surgery, the First Hospital of Peking University from 2010 to 2021 were retrospectively analyzed.Results:The main clinical symptoms were obstructive jaundice, abdominal pain, distension and weight loss. The diagnosis of AIP was confirmed by EUS-FNA in 6 patients,among them, 4 did not relapse after oral hormone treatment, 2 did not receive relevant treatment, and 1 developed gastric cancer one year later. Under a suspicion of malignancy, 9 patients underwent surgical laparotomy ,and the diagnosis was established by pathology. There was no recurrence after oral hormone therapy in 1 patient who underwent laparotomy and pancreatic biopsy. One out of the 3 patients with choledochojejunostomy relapsed after 3 years. Of the 5 patients who underwent pancreatectomy, 4 had no obvious recurrence, and 1 had recurrence after 3 years.Conclusions:Untypical autoimmune pancreatitis is likely to be misdiagnosed as pancreatic cancer. For patients with suspicious malignancy, operational management and biopsy may benefit.
