Survival analysis of proximal gastrectomy in patients with advanced upper gastric cancer
10.3760/cma.j.cn113855-20221130-00744
- VernacularTitle:进展期胃上部癌患者行近端胃切除的预后分析
- Author:
Zhanfei LU
1
;
Hao WANG
;
Xin YIN
;
Junpeng WU
;
Jiaqi ZHANG
;
Yingwei XUE
Author Information
1. 哈尔滨医科大学附属肿瘤医院胃肠外科，哈尔滨 150081
- Keywords:
Stomach neoplasms;
Gastrectomy;
Prognosis
- From:
Chinese Journal of General Surgery
2023;38(4):253-257
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the prognosis difference between proximal gastrectomy (PG) and total gastrectomy (TG) in patients with advanced upper gastric cancer.Methods:This study included patients of upper gastric cancer admitted from Jan 2011 to Dec 2016 undergoing radical resection at Harbin Medical University Cancer Hospital. Patients were divided into TG group (178 cases) and PG group (185 cases).Results:Comapared to PG group , more TG patients were with tumor diameter >4 cm, Borrmann type Ⅲ and postoperative stage Ⅲ ( χ2=9.687, P=0.002; χ2=24.897, P=0.001; χ2=6.257 P=0.044).The 5-year overall survival (OS) of the PG group and the TG group were 64.3% (95% CI: 45.1%-50.5%) and 60.6% (95% CI: 41.3%-47.6%) ( P=0.297).After propensity score matching, the OS between the two groups was not statistically significant ( P=0.876).Subgroup analysis of chemotherapy showed that the difference in survival between TG group and PG group was not statistically significant ( P=0.309). Conclusion:There was no difference in survival between PG and TG in patients with advanced upper gastric cancer.
