Correlation between perioperative new onset atrial fibrillation and prognosis of colorectal cancer
10.3760/cma.j.cn113855-20211028-00619
- VernacularTitle:围手术期新发房颤与结直肠癌预后的关系
- Author:
Kelai YIN
1
;
Shuangming LIN
;
Yibin ZHU
;
Run XIE
;
Zhipeng QUE
;
Runsheng LAI
;
Dongbo XU
Author Information
1. 福建医科大学附属龙岩第一医院胃肠肛门外科，龙岩 364000
- Keywords:
Colorectal neoplasms;
Atrial fibrillation;
C-reactive protein;
Prognosis
- From:
Chinese Journal of General Surgery
2023;38(1):38-43
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the correlation between perioperative new onset atrial fibrillation and the prognosis of colorectal cancer.Methods:This study involved 180 colorectal cancer patients undgoing radical resection at the Department of Gastrointestinal Surgery, Longyan First Hospital from Jan 2014 to Jan 2015. Among them, 47cases suffered from perioperative new onset atrial fibrillation.Results:The perioperative new onset atrial fibrillation group had a higher mean age and a higher mean postoperative C-reactive protein level than the control group ( t=-3.080, P=0.002; t=-2.184, P=0.030). Hence these patients had a longer hospital stay ( t=-5.072, P=0.001; t=-2.577, P=0.011). Multivariate analysis showed that postoperative new onset atrial fibrillation, high postoperative mean C-reactive protein level, poor tumor differenciation and late tumor stage were independent risk factors for the prognosis of colorectal cancer ( HR=1.835, P=0.018; HR=1.008 P=0.017; HR=1.950 P=0.046; HR=1.300, P=0.047). The median survival time of perioperative new onset atrial fibrillation group and control group were 59.05 months and 63.23 months, respectively ( P=0.005). Conclusions:Colorectal cancer patients suffering from perioperative new onset atrial fibrillation were more common among advanced age and high postoperative mean C-reactive protein level with higher all-cause mortality.
