The impact of carbon nanoparticle tracer on the harvested number of lymph nodes in obese gastric cancer patients undergoing radical resection
10.3760/cma.j.cn113855-20220328-00205
- VernacularTitle:纳米碳标记对肥胖胃癌患者根治术淋巴结获取数目的影响
- Author:
Junli ZHANG
1
;
Guoyi SHAO
;
Yangyang HUANG
;
Sen LI
;
Yanghui CAO
;
Chenyu LIU
;
Pengfei MA
;
Changzheng LI
;
Xijie ZHANG
;
Zhenyu LI
;
Yuzhou ZHAO
Author Information
1. 郑州大学附属肿瘤医院(河南省肿瘤医院)普外科，郑州 450000
- Keywords:
Stomach neoplasms;
Lymph nodes;
Nanometer, carbon;
Obesity;
Gastrectomy
- From:
Chinese Journal of General Surgery
2022;37(12):907-910
- CountryChina
- Language:Chinese
-
Abstract:
Object:To investigate the impact of carbon nanoparticle tracing on the number of lymph nodes harvested in obese patients during radical gastrectomy for gastric cancer.Methods:Clinical data of 127 patients undergoing D 2 radical gastrectomy in the Affiliated Tumor Hospital of Zhengzhou University from Jan 2015 to Dec 2019 were retrospectively analyzed. According to whether the patients were injected with carbon nano particles during operation, they were divided into two groups: 64 patients without carbon nano particles during operation served as control group; 63 patients with carbon nano particles were included into experimental group. Results:The operation time of the control group was (160±31) min and that of the experimental group was (168±28) min ( t=-1.521, P=0.445). Intraoperative blood lose in the control group was (234±82) ml and that in the experimental group was (238±84) ml ( t=-0.295, P=0.846). The number of lymph nodes harvested in the first station, in the second station, the number of total lymph nodes and the number of lymph nodes with diameter <5 mm in the control group were less than those in the experimental group(10.4±3.8 vs. 24.5±10.6, t=-10.054),(6.6±2.8 vs. 16.8±7.3, t=-10.381),(17.1±6.4 vs. 41.2±17.6, t=-10.293),(3.9±2.5 vs. 21.2±9.1, t=-14.662) (all P<0.05), while the number of positive lymph nodes was not statistically different between the two groups all (5.9±6.2 vs. 4.2±3.4, t=-1.963, P>0.05). Black staining of lymph nodes in nano carbon group: 1 542 black stained lymph nodes were detected in the experimental group, the black staining rate of lymph nodes was 59.44% (1 542/2 594). Conclusion:Intraoperative application of carbon nanoparticles can significantly increase the number of harvested lymph nodes in obese (BMI≥25 kg/m 2) gastric cancer patients after radical resection.
