Progress in the treatment of chronic spontaneous urticaria: insights from the changes in the understanding of its pathogenesis
10.35541/cjd.20230102
- VernacularTitle:从发病机制认知变化看慢性自发性荨麻疹治疗进展
- Author:
Yunsheng LIANG
1
;
Zhanhong LI
;
Yibei WU
Author Information
1. 南方医科大学皮肤病医院，广州 510091
- Keywords:
Urticaria;
Mast cells;
Immunoglobulin E;
Diagnosis;
Treatment;
Chronic spontaneous urticaria;
Pathogenesis
- From:
Chinese Journal of Dermatology
2023;56(6):552-558
- CountryChina
- Language:Chinese
-
Abstract:
Mast cells, autoantibodies, inflammatory cells, coagulation cascade, complement system and nervous system are all involved in the complex pathogenesis of chronic spontaneous urticaria (CSU) , while mast cells play a pivotal role in it. With deeper understanding of the pathogenesis of CSU, cutting-edge therapeutic methods are gradually being used in clinical practice. Nowadays, pharmacotherapyeutic studies are more focused on accurately modulating the pathological state of mast cells. This review summarizes recent advances in the pathogenesis of and medicines for CSU.
