JAK-STAT signaling pathway and rosacea
- VernacularTitle:JAK-STAT信号通路与玫瑰痤疮
- Author:
Yaling WANG
1
;
Hongfu XIE
;
Ji LI
;
Ben WANG
Author Information
- Keywords: Rosacea; Signal pathway; Neovascularization, pathologic; JAK-STAT signal pathway; Inflammatory factors; Antibacterial peptides
- From: Chinese Journal of Dermatology 2023;56(2):169-172
- CountryChina
- Language:Chinese
- Abstract: Studies have shown that rosacea is related to inflammatory factors, neurovascular function, micro-ecological environment and other factors. The Janus kinase (JAK) -signal transducer and activator of transcription (STAT) signaling pathway involves a variety of inflammatory cytokines, and plays an important role in cell proliferation, differentiation, apoptosis, angiogenesis and immune regulation. This review summarizes the JAK-STAT signaling pathway and explores its potential role in rosacea.
