Risk factors for acute kidney injury after non-cardiac surgery
10.3760/cma.j.cn131073.20220703.01208
- VernacularTitle:非心脏手术患者术后急性肾损伤的危险因素
- Author:
Xinran YU
1
;
Lisong CAI
;
Jingtao YANG
;
Liting ZU
;
Pingxuan GUO
;
Tai WANG
Author Information
1. 华北理工大学附属开滦总医院麻醉科，唐山 063000
- Keywords:
Acute kidney injury;
Postoperative complications;
Risk factors;
Non-cardiac surgery
- From:
Chinese Journal of Anesthesiology
2022;42(12):1452-1455
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To identify the risk factors for acute kidney injury (AKI) after non-cardiac surgery.Methods:Medical records of patients who underwent non-cardiac surgery with general anesthesia in our hospital from October 1, 2016 to March 31, 2021 were collected.AKI was diagnosed using the Kidney Disease Improving Global Outcomes definition of AKI.Multi-factor logistic regression analysis was used to screen the risk factors affecting AKI.Generalized linear regression was used to analyze the factors influencing the difference in serum creatinine before and after surgery.Results:A total of 2 214 patients were eventually enrolled, and the incidence of AKI was 5.15%.The results of multi-factor logistic regression analysis showed that preoperative hypertension, American Society of Anesthesiologists Physical Status classification ≥ Ⅲ, intraoperative bleeding >300 ml, emergency surgery, and grade IV surgery were independent risk factors for AKI after non-cardiac surgery ( P<0.05). The results of generalized line regression analysis showed that preoperative hyponatremia, intraoperative bleeding >300 ml, emergency surgery, and duration of anesthesia were positively correlated with increased difference in serum creatinine before and after surgery ( P<0.05). Conclusions:Preoperative hypertension, American Society of Anesthesiologists Physical Status classification ≥ Ⅲ, intraoperative bleeding >300 ml, emergency surgery and grade IV surgery are independent risk factors for AKI after non-cardiac surgery.
