Efficacy and safety of controlled low central venous pressure applied during hepatectomy: a meta-analysis
10.3760/cma.j.cn131073.20220927.01117
- VernacularTitle:肝切除术中应用控制性低中心静脉压的有效性及安全性：meta分析
- Author:
Xuehan WU
1
;
Lanmei LIANG
;
Kun WEI
;
Tong YUAN
;
Han LI
Author Information
1. 吉林大学第一医院麻醉科，长春 130021
- Keywords:
Hepatectomy;
Hypotension, controlled;
Central venous pressure;
Meta-analysis
- From:
Chinese Journal of Anesthesiology
2022;42(11):1353-1359
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To systematically evaluate the efficacy and safety of controlled low central venous pressure (CLCVP) applied in patients undergoing hepatectomy.Methods:PubMed, Web of Science, Cochrane Library, CNKI, Wanfang, and VIP databases were searched from inception to October 1, 2022 for randomized controlled trials (RCTs) involving CLCVP in hepatectomy.All RCTs enrolled included CLCVP group and conventional operation group.The major evaluation indicators were intraoperative blood loss, operation duration and intraoperative blood transfusion.The secondary evaluation indicators were intraoperative monitoring indicators, postoperative liver and renal function, and complications at 1 day after operation.Meta-analysis was performed using the RevMan 5.3 software.Results:A total of 25 RCTs involving 1 816 patients were finally included.Compared with conventional operation group, the intraoperative blood loss was significantly reduced, the operation time was shorten, the rate of intraoperative blood transfusion was decreased, the amount of blood transfused was decreased ( P<0.01), and no significant change was found in intraoperative hemodynamic parameters and parameters of liver and renal function at 1 day after operation, and incidence of gas embolism, pleural effusion and bile leakage in CLCVP group ( P>0.05). Conclusions:CLCVP is safe and effective during hepatectomy.
