Research updates of functional nanomaterials in the prevention and treatment of renal calcium oxalate stones
10.3760/cma.j.cn112330-20221220-00672
- VernacularTitle:功能性纳米材料在肾草酸钙结石防治中的研究进展
- Author:
Wenzhe CHEN
1
;
Hongxing LIU
;
Guohua ZENG
Author Information
1. 广州医科大学附属第一医院泌尿外科 广东省泌尿外科重点实验室,广州 510230
- Keywords:
Kidney calculi;
Calcium oxalate;
Nanomaterials;
Treatment;
Prevention
- From:
Chinese Journal of Urology
2023;44(4):313-316
- CountryChina
- Language:Chinese
-
Abstract:
Although great progress has been made in the treatment of renal calcium oxalate stones, the incidence and recurrence rate are still high. Functional nanomaterials refer to nanomaterials with specific functions after physical or chemical action.Their role in the treatment of renal calcium oxalate stones has been widely recognized in recent years. Functional nano-materials can be divided into nano-enzymes, nano-drugs and nano-carriers according to their functions. Nano-enzymes and nano-drugs can prevent and treat calcium oxalate kidney calculi by using their physical and chemical properties or drugs. Nano-carriers can treat kidney stones by delivery of the drugs. The purpose of this paper is to describe the application of functional nanomaterials in the prevention and treatment of renal calcium oxalate stones, to summarize the mechanism of inhibiting the formation of renal calcium oxalate stones and the direction of clinical treatment in the future.