Advances in the study of the correlation between urolithiasis and non-alcoholic fatty liver disease
10.3760/cma.j.cn112330-20220609-00350
- VernacularTitle:泌尿系结石与非酒精性脂肪性肝病相关性的研究进展
- Author:
Shengqi ZHENG
1
;
Guicao YIN
;
Lingyu LI
;
Xiang PAN
;
Xiaoxiang WANG
;
Yifan LI
Author Information
1. 扬州大学附属医院泌尿外科，扬州 225009
- Keywords:
Urolithiasis;
Non-alcoholic fatty liver disease;
Metabolic syndrome
- From:
Chinese Journal of Urology
2023;44(2):157-160
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, researchers have found that patients with nonalcoholic fatty liver disease (NAFLD) often have urolithiasis, and the incidence of urolithiasis increases gradually with the severity of NAFLD. Meanwhile, the detection rate of NAFLD was higher in patients with urolithiasis than in normal controls. In this paper, we reviewed the domestic and international studies on the correlation between urolithiasis and NAFLD and described the related pathogenesis, such as insulin resistance, oxidative stress, abnormal lipid metabolism and impaired glyoxalate detoxification. Meanwhile, this paper proposed preventive measures to reduce the risk of development and recurrence of NAFLD-associated urolithiasis by addressing the common risk factors of both diseases, including metabolism-related diseases, lifestyle and diet.
