Research progress of immune vaccines in the prevention of recurrent urinary tract infections
10.3760/cma.j.cn112330-20220810-00458
- VernacularTitle:免疫疫苗预防反复发作尿路感染的研究进展
- Author:
Xi ZHANG
1
;
Qiang GUO
;
Jiahui CHEN
;
Zhenxing WANG
;
Chengyong LI
;
Kexin YAN
;
Yijun WANG
;
Minghe XIE
;
Haoying SHI
;
Chuan HAO
Author Information
1. 山西医科大学第二医院/第二临床医学院泌尿外科，太原 030001
- Keywords:
Recurrent urinary tract infection;
Vaccines;
Immunity mechanism
- From:
Chinese Journal of Urology
2022;43(10):793-796
- CountryChina
- Language:Chinese
-
Abstract:
Urinary tract infection (UTI) is one of the most common infectious diseases. It has the characteristics of high recurrence rate and prolonged course. At present, the problem of antibiotic resistance is becoming more and more serious, the incidence of adverse reactions is high, and the disadvantages of long-term administration appear, which brings severe challenges to the treatment of recurrent urinary tract infection. The prevention and treatment of UTI recurrence has become the focus of research. Recurrent urinary tract infection is related to the immune regulation mechanism of the body. Administration of immune regulation can provide new ideas for prevention and treatment. The vaccine based on immune regulation to prevent rUTI has made some progress. It can not only reduce the frequency of recurrences, but also decrease related symptoms. At the same time, the vaccine has good tolerance, high safety and good application prospect. This paper aims to summarize the progress of immune regulation and immune vaccines in vivo and clinical research.
