Early implementation of group rehabilitation exercise improves quality of life in patients with Parkinson's disease
10.3760/cma.j.issn.0254-9026.2023.06.005
- VernacularTitle:早期团体康复运动改善帕金森病患者的生活质量探讨
- Author:
Yang YANG
1
,
2
;
Tianyu JIANG
;
Lifeng CHEN
;
Jiarui YAO
;
Na WANG
;
Dandan LIU
;
Dongmei LI
;
Dan LIU
;
Weiping WU
;
Zhongbao GAO
;
Zhenfu WANG
Author Information
1. 中国人民解放军总医院第二医学中心&
2. 国家老年疾病临床医学研究中心神经内科，北京 100086
- Keywords:
Parkinson's disease;
Exercise;
Group exercise;
Targeted exercise;
Rehabilitation
- From:
Chinese Journal of Geriatrics
2023;42(6):645-649
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the impact of group-based rehabilitation exercise on motor and non-movement symptoms of Parkinson's disease(PD).Methods:A total of 88 patients from out-patient and in-patient services at our hospital were randomly assigned to an early exercise group(E-EG), a late exercise group(L-EG), and a control group(CG)using a randomized delayed-start design.Patients in the E-EG carried out a rigorous, formal group exercise program, one hour per session, twice per week, for 18 months(May 2018-November 2019). Patients in the L-EG took part in the exercise program in the final 6-12 months of the study.We assessed outcomes using the Unified Parkinson's Disease Rating Scale(UPDRS), Parkinson's disease questionnaire-39(PDQ-39 Q), trail-making test part A & B, nine-hole peg test(9-HPT), 30 second sit to stand test(30s SST), 10 m walk test(10 m W), mini-balance evaluation systems test(Mini-BEST), Fullerton Advanced Balance(FAB)Scale and time up and go(TUG)test.Results:Compared with pre-exercise levels, patients with PD in the E-EG had lower performance in UPDRS(17.5±8.3 vs.20.0±8.6, t=-2.2, P=0.02)and lower performance in PDQ-39(27.2±2.1 vs.29.0±9.8, t=-2.6, P=0.001)after exercise.Moreover, compared with pre-exercise levels, patients with PD in the E-EG showed decreased post-exercise performance in trail-making test part B(114.2±25.5 vs.129.8±28.4, t=-2.3, P=0.02)and in 9-HPT(33.7±7.3 vs.39.6±9.3, t=-2.6, P=0.001). Conclusions:The practice of group-based rehabilitation exercise can improve movement abilities and quality of life in PD patients, especially if implemented early.Targeted rehabilitation exercise should be taken as part of the treatment strategy for PD patients as early as possible to deliver the best benefits.
