Anemia on the prognosis of elderly patients with acute coronary syndrome: a meta-analysis
10.3760/cma.j.issn.0254-9026.2023.04.015
- VernacularTitle:老年急性冠状动脉综合征患者贫血对预后影响的系统评价
- Author:
Chu FAN
1
;
Ji HUANG
;
Hangyu YAN
;
Dan LI
;
Zhizhong LI
;
Yutong CHENG
;
Zhao LI
;
Nan LI
Author Information
1. 首都医科大学附属北京安贞医院心内科十五病房 100029
- Keywords:
Coronary artery disease;
Anemia;
Prognosis;
Meta-analysis
- From:
Chinese Journal of Geriatrics
2023;42(4):458-462
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To examine the effect of anemia on the prognosis of elderly patients with acute coronary syndrome.Methods:We searched PubMed, Scopus, OVID, the Cochrane Library, Web of Science, Embase, China National Knowledge Infrastructure, China Biology Medicine Disc, the WanFang and Weipu databases for studies on the association between anemia and the prognosis of acute coronary syndrome in elderly patients.The date range included the period from the establishment of the database to December 10, 2022.Two reviewers independently completed the literature screening and data extraction according to the inclusion and exclusion criteria for the literature.Stata 16.0 software was used to analyze the data.Results:Of 1 399 references retrieved from the initial search, 13 met the inclusion criteria, including a total of 9540 patients with a mean age of 70.3 years.2872 of these patients had concurrent anemia and 6 668 patients had no anemia.In elderly patients with acute coronary syndrome, those with anemia showed significantly increased risk of death, compared with those with no anemia( RR=2.28, 95% CI: 1.74-3.00). Anemia also increased the incidence of ischemia( RR=1.36, 95% CI: 1.13-1.64)and bleeding events( RR=2.18, 95% CI: 1.59-3.01)( P<0.05 for all). Conclusions:Anemia significantly increases the risk of death and is associated with poor prognosis in elderly patients with acute coronary syndrome.
