Mechanisms of the acute kidney injury to chronic kidney disease transition
10.3760/cma.j.issn.0254-9026.2023.02.019
- VernacularTitle:急性肾损伤转化为慢性肾脏病的机制
- Author:
Hui ZHANG
1
;
Binbin PAN
;
Xin WAN
Author Information
1. 南京医科大学附属南京医院（南京市第一医院）肾内科，南京 210006
- Keywords:
Acute kidney injury;
Chronic kidney disease;
Mechanism;
Pathophysiology
- From:
Chinese Journal of Geriatrics
2023;42(2):234-238
- CountryChina
- Language:Chinese
-
Abstract:
Acute kidney injury(AKI)is a common clinical pathophysiological phenomenon, which is characterized by high morbidity, ICU hospitalization rate and mortality.In addition, AKI is an independent risk factor for chronic kidney disease(CKD)and end-stage renal disease.A number of studies have revealed various mechanisms involved in the transition of AKI to CKD, but there is still no breakthrough in effective prevention and treatment.This article reviews the mechanisms of transition from AKI to CKD, and expects to provide potential targets for further intervention.
