Research progress of ferroptosis in aortic dissection
10.3760/cma.j.issn.0254-9026.2023.02.018
- VernacularTitle:铁死亡在主动脉夹层中的研究进展
- Author:
Yaoyao WU
1
;
Na LI
;
Minghui SUN
;
Bingxiang WANG
;
Zhimian ZHANG
Author Information
1. 山东大学齐鲁医院健康管理中心,济南 250012
- Keywords:
Myocytes, Smooth muscle;
Endothelial cell;
Extracellular matrix;
Ferroptosis;
Aortic dissection
- From:
Chinese Journal of Geriatrics
2023;42(2):229-233
- CountryChina
- Language:Chinese
-
Abstract:
Aortic dissection, especially Stanford type A aortic dissection, is an acutely progressive and highly fatal cardiovascular disease.Early prevention and timely treatment can greatly reduce mortality and reduce the burden on families and society.However, due to the etiological mechanism is still unclear, the clinical treatment is still mainly surgery, and the early prevention and drug application are very limited.And some recent studies have found that ferroptosis may play an important role in the occurrence and development of aortic dissection, revealing the relationship between them may provide ideas for the prevention, treatment and scientific research of the disease.