Association between Helicobacter pylori infection and albuminuria among physical examination population
10.3760/cma.j.cn115624-20230115-00030
- VernacularTitle:健康体检人群幽门螺杆菌感染与白蛋白尿的相关性
- Author:
Wen GAO
1
;
Zhengce WAN
;
Yuchai HUANG
;
Xiaomei LEI
;
Yuancheng HUANG
;
Liu HU
Author Information
1. 华中科技大学同济医学院附属同济医院体检中心，武汉 430030
- Keywords:
Helicobacter pylori;
Physical examination;
Albuminuria
- From:
Chinese Journal of Health Management
2023;17(8):598-602
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the correlation between Helicobacter pylori ( H.pylori) infection and albuminuria inphysical examination population. Methods:It was a cross-sectional study. All the adults who received physical examination and underwent 13C-urea breath test at the Physical Examination Center in Tongji Hospital in 2021 were selected as the study subjects. General data (such as demographic information and past medical history) were documented. The physical measurement and blood biochemical indicators were checked too. Multivariate analysis was used to analyze the relationship between H. pylori infection and albuminuria. Results:A total of 30 311 subjects were included in this analysis. There were 17 123 males and 13 188 females with an age of (44.51±12.17) years. The positive rate of H. pylori infection was 27.3%. The incidence of albuminuria in subjects with H. pylori infection was 6.7%, and it was 6.1% in the subjects without H. pylori infection ( P=0.031). After adjusting for the confounding factors such as gender, age, diabetes and hypertension, H. pylori infection was independently associated with the risk of albuminuria (odds ratio ( OR)=1.133, 95% CI: 1.018-1.261, P=0.022). Conclusion:H. pylori infection is positively correlated with the occurrence of albuminuria in the physical examination population.
