Association between appendicular skeletal muscle mass and ankle-brachial index in patients with type 2 diabetes
10.3760/cma.j.cn115624-20220525-00399
- VernacularTitle:2型糖尿病患者四肢骨骼肌量与踝肱指数的相关性
- Author:
Qing HAN
1
;
Lili LIU
;
Ye PAN
;
Bingquan YANG
;
Juan XU
;
Hua HE
;
Zilin SUN
;
Shanhu QIU
Author Information
1. 东南大学附属中大医院内分泌科，南京 210009
- Keywords:
Diabetes mellitus, type 2;
Appendicular skeletal muscle mass;
Ankle-brachial index
- From:
Chinese Journal of Health Management
2023;17(1):36-40
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To assess the relationship between appendicular skeletal muscle mass (ASM) and ankle brachial index (ABI) among patients with type 2 diabetes.Methods:In this cross-sectional study, from July 2018 to March 2019, a total of 278 patients with type 2 diabetes treated in Zhongda Hospital were enrolled in this study, and there were 158 males and 120 females. General information and clinical biochemical parameters and ABI in the patients were collected. The appendicular muscle mass was quantitatively measured with body composition analyzer to achieve ASM. And the appendicular skeletal muscle mass index (ASMI), skeletal muscle index (SMI), and appendicular skeletal muscle mass/body mass index (ASM/BMI) were calculated respectively. Correlation analysis and multiple linear regression analyses with different adjustment models were conducted to analyze the correlation between ABI and above-mentioned indexes.Results:The Pearson correlation analysis showed that ABI had significant positive correlation with ASM, ASMI and ASM/BMI ( r=0.14, 0.13, 0.13, all P<0.05), but a marginal relation with SMI ( r=0.116, P=0.053). Multiple linear regression analysis suggested that ASMI ( β=0.053, 95% CI: 0.006-0.101, P=0.027) and AMI/ABI ( β=0.347, 95% CI: 0.040-0.654, P=0.027) were significantly related to ABI. Conclusion:ASM is positively associated with ABI in patients with type 2 diabetes.
