Efficacy and safety of laparoscopic surgery in treatment of recurrent hepatocellular carcinoma
10.3760/cma.j.cn113884-20220820-00341
- VernacularTitle:腹腔镜手术治疗复发性肝癌的安全性和疗效分析
- Author:
Linhuan LI
1
;
Zheng SONG
;
Fen ZHOU
;
Bingzhang TIAN
;
Fangming WANG
;
Jun WANG
;
Pin LYU
;
Gang LIANG
;
Ye OU
Author Information
1. 湖南师范大学附属第一医院（湖南省人民医院）肝胆外科，长沙 410005
- Keywords:
Liver neoplasms;
Recurrent;
Laparoscopic hepatectomy
- From:
Chinese Journal of Hepatobiliary Surgery
2023;29(1):38-42
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the efficacy and safety of laparoscopic surgery in treatment of recurrent hepatocellular carcinoma.Methods:The clinical data of 58 patients with recurrent hepatocellular carcinoma who underwent surgical treatment from January 2010 to January 2018 at Hunan Provincial People’s Hospital were retrospectively analyzed. There were 50 males and 8 females, ranging in age from 28 to 78 (53.0±10.8) years old. Patients were divided into laparoscopic group ( n=27) and laparotomy group ( n=31) according to different surgical procedures. The differences in operative time, intraoperative blood loss, hospital stay, postoperative anal exhaustion time, postoperative complications and prognosis between the two groups were compared. Results:The intraoperative blood loss of laparoscopy group and laparotomy group were 100.0(50.0, 400.0) ml vs 300.0(100.0, 500.0) ml, the postoperative anal exhaustion time were (2.7±0.6) d vs (3.3±0.6) d, the hospital stay were (14.8±3.8) d vs (21.4±6.3) d, and these differences were statistically significant (all P<0.05). The operative time of the two groups were (243.4±27.2) min vs (217.5±34.7) min, with no statistical significance ( t=0.59, P=0.344). There were no significant differences between the two groups in postoperative complications (bile leakage, abdominal infection, hemorrhage, pleural effusion and hepatic encephalopathy) (all P>0.05); thetumor free survival, 1-year, and 3-year overall survival rates of the two groups were also not significantly different (both P>0.05). Conclusion:Laparoscopic surgery is safe and effective in the treatment of recurrent hepatocellular carcinoma, and its prognosis is similar to laparotomy, its complications are not significantly increased, which is worthy of promotion in clinic.
