Research progress on the effect of hyperthermia on vascular endothelial growth factor in tumor microenvironment

VernacularTitle:热疗对肿瘤微环境中VEGF作用的研究进展
Author: Yuan CONG ¹ ; Yun SHAO ; Xuexiao ZHOU ; Pei SHEN ; Shengzhi WANG
Author Information

1. 青岛大学口腔医学院，青岛　266003
Keywords: Vascular endothelial growth factor; Neoplasms / hyperthermia; Tumor microenvironment; Tumor immune microenvironment
From: Chinese Journal of Radiation Oncology 2023;32(8):736-741
CountryChina
Language:Chinese
Abstract: Vascular endothelial growth factor (VEGF) plays an important role in promoting tumor vascular growth and changing vascular wall permeability. With the in-depth study of tumor hyperthermia and tumor microenvironment, more and more studies have shown that hyperthermia exerts multiple regulatory effects on VEGF in tumor microenvironment. Combined with current research progress in China and abroad, this article reviews the effect of hyperthermia on VEGF and its related cells and factors in tumor microenvironment, aiming to provide new ideas for the clinical application of tumor hyperthermia combined with immune or targeted therapy.