Clinical application and prospect of SBRT in treatment of oligo-metastatic NSCLC

VernacularTitle:体部立体定向放疗在寡转移NSCLC的临床应用和前景
Author: Min FANG ¹ ; Xianghui DU ; Xiaojing LAI
Author Information

1. 浙江省肿瘤医院胸部放疗科，中国科学院杭州医学研究所，杭州　310022
Keywords: Carcinoma, non-small-cell lung; Oligo -metastasis; Stereotactic body radiation therapy
From: Chinese Journal of Radiation Oncology 2023;32(7):633-637
CountryChina
Language:Chinese
Abstract: The rapid progress on immunotherapy and targeted therapy has brought long-term survival benefits for locally advanced non-small cell lung cancer (NSCLC). The oncology community has also paid more attention to the local treatment for advanced NSCLC, especially for patients with limited metastatic lesions, also known as oligo-metastasis. Many studies have reported that oligo-metastatic NSCLC patients could benefit from the combination of local and systematic treatment, and even to be cured. In recent years, with the advances in radiation technology, stereotactic body radiation therapy (SBRT) has achieved precise high-dose radiotherapy for small target tumors. Currently, SBRT has been widely applied in the treatment of inoperable early lung cancer, and its application value and safety in patients with advanced lung cancer are also being actively explored. In this article, the research status, progress and future development direction of SBRT in the treatment of oligo-metastatic NSCLC were discussed.