Research progress on tumor treating fields combined with radiation therapy in the treatment of glioblastoma

VernacularTitle:肿瘤电场治疗联合同步放疗治疗胶质母细胞瘤研究进展
Author: Qiao QIAO ¹ ; Huiyu XIAO ; Guang LI
Author Information

1. 中国医科大学附属第一医院放射治疗科，沈阳　110002
Keywords: Glioblastoma; Tumor / treating fields; Radiotherapy; Simultaneous combination therapy
From: Chinese Journal of Radiation Oncology 2023;32(4):370-374
CountryChina
Language:Chinese
Abstract: For patients with newly diagnosed glioblastoma, tumor treating fields (TTF) combined with temozolomide after radiation therapy is currently one of the standard therapeutic regimens. Recently, TTF has been increasingly applied in combination with radiation therapy since it can delay tumor DNA repair and increase DNA replication stress. The efficacy of TTF has been proven in clinical studies. However, no consensus has been reached regarding the theoretical basis, radiation dose, actual clinical operation, patients' benefit and safety, which remain controversial. In this article, research progress on these topics was reviewed.