Research progress on radio-resistance mechanism of nasopharyngeal carcinoma
10.3760/cma.j.cn113030-20211224-00525
- VernacularTitle:鼻咽癌放射治疗抵抗机制研究进展
- Author:
Zhenyu YAN
1
;
Xiang CAO
;
Xinyu HU
;
Yizhi GE
;
Dan ZONG
;
Xia HE
Author Information
1. 南京医科大学附属肿瘤医院，江苏省肿瘤医院，江苏省肿瘤防治研究所，南京 210009
- Keywords:
Nasopharyngeal carcinoma;
Radio-resistance;
Radiosensitivity
- From:
Chinese Journal of Radiation Oncology
2023;32(3):281-286
- CountryChina
- Language:Chinese
-
Abstract:
Nasopharyngeal carcinoma is one of the most common malignant head and neck tumors, and radiotherapy is the main treatment. However, radio-resistance is a key cause of local recurrence of nasopharyngeal carcinoma. Therefore, overcoming the radio-resistance of nasopharyngeal carcinoma and enhancing the radiosensitivity have become urgent problems in the treatment of nasopharyngeal carcinoma, which also play a key role in improving the overall survival rate of patients. In this article, recent studies on DNA, non-coding RNA (ncRNA), protein and cell behaviors related to radio-resistance of nasopharyngeal carcinoma were reviewed, aiming to provide valuable ideas for clinical treatment of nasopharyngeal carcinoma.
