Exploration of feasible total neoadjuvant therapy for locally advanced esophageal squamous cell carcinoma
10.3760/cma.j.cn113030-20210923-00369
- VernacularTitle:局部进展期食管鳞癌全新辅助治疗可行方案的探索
- Author:
Jingyuan WEN
1
;
Wenbin SHEN
;
Shuchai ZHU
Author Information
1. 河北医科大学第四医院放疗科，石家庄 050011
- Keywords:
Esophageal squamous cell carcinoma;
Locally advanced stage;
Total neoadjuvant therapy;
Exploration
- From:
Chinese Journal of Radiation Oncology
2023;32(1):65-69
- CountryChina
- Language:Chinese
-
Abstract:
Neoadjuvant radiotherapy and chemotherapy combined with surgery is the standard treatment for patients with locally advanced esophageal cancer, which has been widely applied in clinical practice. Clinical efficacy has also been recognized by clinicians. However, even after the completion of neoadjuvant radiotherapy and subsequent surgical treatment, some patients still have local regional recurrence or distant metastasis in a short period of time. Among them, distant metastasis has become the main failure mode of patients undergoing surgery after neoadjuvant radiotherapy and chemotherapy, indicating that this treatment remains to be further improved. Based on the experience of patients with rectal cancer benefiting from total neoadjuvant therapy, the feasibility and implementation of total neoadjuvant therapy for locally advanced esophageal cancer were discussed in this article.
