Development of dose verification methods for boron neutron capture therapy
10.3760/cma.j.cn112271-20221115-00448
- VernacularTitle:硼中子俘获治疗剂量验证方法进展
- Author:
Jun GAO
1
;
Yadi ZHU
;
Yongfeng WANG
;
Chufeng JIN
;
Xiang JI
Author Information
1. 中子科学国际研究院,青岛 266199
- Keywords:
Boron neutron capture therapy;
Neutron dose measurement;
Dose verification
- From:
Chinese Journal of Radiological Medicine and Protection
2023;43(3):228-233
- CountryChina
- Language:Chinese
-
Abstract:
To summarize the progress in BNCT dose verification method in the world and discusses their development prospects. Boron neutron capture therapy (BNCT) utilizes the specific capture reaction between the neutrons and boron drugs enriched in tumor cells to selectively kill tumor cells. In order to verify the accuracy of the radiotherapy plan and ensure the therapeutic effect on patients, it is necessary to measure the dose before treatment and compare the experimental radiation dose with the planned dose. The current BNCT dose measurement method mainly include point dose measurement method based on ionization chambers, thermoluminescence dosimeters and activation foils, two-dimensional dose measurement method based on films, and three-dimensional dose measurement method based on gel dosimeters.