A Case of Primary Cutaneous Plasmacytoma.
- Author:
Daehwan KIM
1
;
Kyeong Han YOON
Author Information
1. Department of Dermatology, Ajou University School of Medicine, Suwon, Korea. yoon_skin@yahoo.co.kr
- Publication Type:Case Report
- Keywords:
Primary cutaneous plasmacytoma;
Monoclonality;
Lambda chain
- MeSH:
Bone Marrow;
Clone Cells;
Diagnosis;
Electrophoresis;
Humans;
Immunoglobulins;
Lymphoma, B-Cell;
Multiple Myeloma;
Neck;
Plasma Cells;
Plasmacytoma*;
Prognosis;
Skin;
Young Adult
- From:Korean Journal of Dermatology
2002;40(4):405-409
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Primary cutaneous plasmacytoma is a rare cutaneous B cell lymphoma characterized by monoclonal proliferation of mature plasma cells in the skin without systemic involvement. Although a significant proportion of patients, especially with multiple lesions, went on to develop systemic disease with a poor prognosis, the abnormal clone of plasma cells may arise in the skin and never progress to multiple myeloma involving the bone marrow in a number of patients. We report a case of primary cutaneous plasmacytoma and review data published in the literature. A 19-year-old man developed multiple 0.2 to 0.5cm sized erythematous grouped papules on his posterior neck for 4 years. Histopathologic examination represented superficial and deep interstitial and nodular dense infiltration of plasma cells showing monoclonal expression of immunoglobulin lambda light chain. F-18 FDG coincidence PET(CoDe-PET) scan and serum electrophoresis were within normal limit. Any systemic disease has not developed for 6 months after diagnosis.
