Effect of preoperative pulmonary hypertension on right ventricular function of cardiac allograft assessed by two-dimensional speckle tracking echocardiography
10.3760/cma.j.cn131148-20220330-00216
- VernacularTitle:二维斑点追踪超声心动图评价术前肺动脉高压对移植心脏右室功能的影响
- Author:
Xin ZHANG
1
;
Shuangshuang ZHU
;
Wenqian WU
;
He LI
;
Lingyun FANG
;
Manwei LIU
;
Yi ZHOU
;
Yang ZHAO
;
Li ZHANG
;
Yuman LI
;
Guohua WANG
;
Shu CHEN
;
Nianguo DONG
;
Mingxing XIE
Author Information
1. 华中科技大学同济医学院附属协和医院超声医学科 湖北省影像医学临床医学研究中心 分子影像湖北省重点实验室，武汉 430022
- Keywords:
Echocardiography;
Speckle tracking imaging;
Heart transplantation;
Hypertension, pulmonary;
Ventricular function, right
- From:
Chinese Journal of Ultrasonography
2022;31(12):1013-1020
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of preoperative pulmonary hypertension (PH) on right ventricular function in patients with heart transplantation(HTx) one year after surgery.Methods:A total of 120 patients who underwent HTx in Union Hospital, Tongji Medical College, Huazhong University of Science and Technology from January 2017 to January 2020 were retrospectively recruited.According to the mean pulmonary arterial pressure (mPAP) obtained by preoperative right heart catheterization, the research subjects were divided into the pulmonary hypertension group (PH group, n=81) and without pulmonary hypertension group (NPH group, n=39). Conventional echocardiographic indices of right ventricular function such as right ventricular area change (RV-FAC), tricuspid annular plane systolic excursion (TAPSE), tricuspid lateral annular systolic velocity (S′), and two-dimensional speckle tracking imaging (2D-STI) strain parameters including right ventricular global longitudinal strain (RV-GLS), right ventricular free wall longitudinal strain (RV-FWLS) were obtained to assess the right ventricular function of grafted hearts. The echocardiographic parameters one year after the operation of the two groups were analyzed to compare the differences in right ventricular function and their correlation with preoperative mPAP. Results:The grafted heart RV-GLS and RV-FWLS were significantly decreased in the PH group (all P<0.01), while RV-FAC, TAPSE, and S′ were similar between the two groups (all P>0.05). RV-FWLS and RV-GLS correlated with preoperative hemodynamic parameter mPAP( rs=-0.46, -0.54; all P<0.05)while RV-FAC, TAPSE, and S′ were not significantly correlated with mPAP (all P>0.05). Conclusions:Preoperative PH correlates with right ventricular function in HTx patients 1 year after the operation. The absolute values of RV-FWLS and RV-GLS in HTx patients with preoperative PH decrease 1 year after the operation. 2D-STI is more sensitive than conventional echocardiography to monitor the changes in right ventricular function in HTx patients after the operation.
