Evaluation of diastolic left ventricular relative pressure in patients with type 2 diabetes mellitus by vector flow mapping
10.3760/cma.j.cn131148-20220324-00196
- VernacularTitle:血流向量成像技术评价2型糖尿病患者舒张期左心室内相对压
- Author:
Danqing HUANG
1
;
Cunying CUI
;
Yanan LI
;
Yuanyuan LIU
;
Yanbin HU
;
Ying WANG
;
Ruijie LIU
;
Lin LIU
Author Information
1. 阜外华中心血管病医院超声科 郑州大学华中阜外医院 河南省人民医院 郑州大学人民医院，郑州 451464
- Keywords:
Vector flow mapping;
Type 2 diabetes mellitus;
Relative pressure imaging;
Left intraventricular pressure difference;
Ventricular function, left
- From:
Chinese Journal of Ultrasonography
2022;31(11):933-939
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the distribution of diastolic left ventricular pressure in patients with type 2 diabetes mellitus (T2DM) by relative pressure imaging (RPI) based on vector flow mapping (VFM), and to explore the clinical risk factors for the diastolic left ventricular pressure distribution.Methods:Thirty patients with T2DM and thirty normal controls were included from August 2020 to July 2021 in Fuwai Central China Cardiovascular Hospital. All selected subjects underwent conventional echocardiography.Left intraventricular pressure difference (IVPD) and left intraventricular pressure gradient (IVPG) were measured using RPI of VFM in isovolumic relaxation (IR), rapid filling (RF), atrial contraction (AC), isovolumic contraction (IC) and rapid ejection (RE) phases. The relationships between IVPD with other parameters were analyzed.Results:①Compared with the control group, E/A, e′, IVPD-IR, IVPG-IR, IVPD-RF, IVPG-RF, IVPD-AC, and IVPG-AC were significantly lower and E/e′ was significantly greater in the T2DM group ( P<0.05). ②IVPD-IR, IVPD-RF, and IVPD-AC were positively correlated with E/A ( r=0.309, P<0.05; r=0.274, P<0.05; r=0.273, P<0.05). IVPD-IR, IVPD-RF, and IVPD-AC were negatively correlated with E/e′ ( r=-0.587, P<0.05; r=-0.273, P<0.05; r=-0.415, P<0.05). IVPD-IR and IVPD-AC were positively correlated with e′ ( r=0.451, P<0.05; r=0.431, P<0.05). ③Multivariable linear regression analysis showed that hemoglobin A 1c (HbA 1c) was an independent risk factor affecting IVPD-IR, IVPD-RF, and IVPD-AC (β=-0.417, P<0.05; β=-0.451, P<0.05; β=-0.460, P<0.05). Conclusions:RPI of VFM can quantitatively evaluate diastolic left ventricular pressure distribution in patients with T2DM. HbA 1c is an independent risk factor affecting IVPD-IR, IVPD-RF, and IVPD-AC.
