An evidence-based clinical guideline for the treatment of infectious bone defect with induced membrane technique (version 2023)
- VernacularTitle:膜诱导技术治疗感染性骨缺损临床循证指南（2023版）
- Author:
Jie SHEN
1
;
Lin CHEN
;
Shiwu DONG
;
Jingshu FU
;
Jianzhong GUAN
;
Hongbo HE
;
Chunli HOU
;
Zhiyong HOU
;
Gang LI
;
Hang LI
;
Fengxiang LIU
;
Lei LIU
;
Feng MA
;
Tao NIE
;
Chenghe QIN
;
Jian SHI
;
Hengsheng SHU
;
Dong SUN
;
Li SUN
;
Guanglin WANG
;
Xiaohua WANG
;
Zhiqiang WANG
;
Hongri WU
;
Junchao XING
;
Jianzhong XU
;
Yongqing XU
;
Dawei YANG
;
Tengbo YU
;
Zhi YUAN
;
Wenming ZHANG
;
Feng ZHAO
;
Jiazhuang ZHENG
;
Dapeng ZHOU
;
Chen ZHU
;
Yueliang ZHU
;
Zhao XIE
;
Xinbao WU
;
Changqing ZHANG
;
Peifu TANG
;
Yingze ZHANG
;
Fei LUO
Author Information
- Keywords: Bone; Infection; Debridement; Bone transplantation; Guideline
- From: Chinese Journal of Trauma 2023;39(2):107-120
- CountryChina
- Language:Chinese
- Abstract: Infectious bone defect is bone defect with infection or as a result of treatment of bone infection. It requires surgical intervention, and the treatment processes are complex and long, which include bone infection control,bone defect repair and even complex soft tissue reconstructions in some cases. Failure to achieve the goals in any step may lead to the failure of the overall treatment. Therefore, infectious bone defect has been a worldwide challenge in the field of orthopedics. Conventionally, sequestrectomy, bone grafting, bone transport, and systemic/local antibiotic treatment are standard therapies. Radical debridement remains one of the cornerstones for the management of bone infection. However, the scale of debridement and the timing and method of bone defect reconstruction remain controversial. With the clinical application of induced membrane technique, effective infection control and rapid bone reconstruction have been achieved in the management of infectious bone defect. The induced membrane technique has attracted more interests and attention, but the lack of understanding the basic principles of infection control and technical details may hamper the clinical outcomes of induced membrane technique and complications can possibly occur. Therefore, the Chinese Orthopedic Association organized domestic orthopedic experts to formulate An evidence-based clinical guideline for the treatment of infectious bone defect with induced membrane technique ( version 2023) according to the evidence-based method and put forward recommendations on infectious bone defect from the aspects of precise diagnosis, preoperative evaluation, operation procedure, postoperative management and rehabilitation, so as to provide useful references for the treatment of infectious bone defect with induced membrane technique.
