Research progress on physiological and pathological effects of inflammation in female reproductive process
10.3760/cma.j.cn101721-20230221-000062
- VernacularTitle:炎症在女性生殖过程中的生理及病理作用研究进展
- Author:
Xianghua DONG
1
;
Jiajia LIU
;
Mingxia GAO
Author Information
1. 兰州大学第一临床医学院，兰州 730000
- Keywords:
Inflammation;
Reproduction;
Metabolism
- From:
Clinical Medicine of China
2023;39(4):316-320
- CountryChina
- Language:Chinese
-
Abstract:
Inflammation is the basic pathological process of a variety of diseases, which involved in the occurrence and development of female infertility-related diseases, especially in bacteria and viruses infection of reproductive system, resulting in infertility. However, inflammatory reactions and factors also exist in normal physiological processes, such as endometrial morphologic changes in menstrual cycles, follicle genesis, ovulation, luteinization, pregnancy, etc. In addition, inflammation is also involved in the occurrence of some reproductive endocrine and metabolic diseases, such as obesity, endometriosis, polycystic ovary syndrome and so on. In the past, the understanding to inflammation in reproductive system was mostly limited to the inflammatory diseases and resulted in fertility decline or sterility, infertility, and other problems, which was not comprehensive. This review summarized the normal physiological inflammation and disease-related inflammation in the reproductive system, and described the evaluation of inflammatory state, as well as relevant prevention and treatment suggestions.
