Diagnosis and treatment of negative pressure hydrocephalus: analysis of 5 cases and literature review
10.3760/cma.j.cn101721-20221017-000474
- VernacularTitle:负压性脑积水的诊治5例分析及文献复习
- Author:
Tao SUN
1
;
Qingyin LIU
;
Ke PU
;
Guoqing HAN
;
Qingguo LI
Author Information
1. 天津市西青医院神经外科，天津 300000
- Keywords:
Negative pressure hydrocephalus;
obstructive hydrocephalus;
Cisternography Third ventriculostomy
- From:
Clinical Medicine of China
2023;39(4):281-287
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the clinical manifestations, pathogenesis,diagnosis and treatment of negative pressure hydrocephalus (NPH).Methods:A retrospective analysis was performed on the 5 patients with NPH admitted to the Department of Neurosurgery, Tianjin Huanhu Hospital from January 2019 to December 2021. All of the patients underwent lumbar puncture and ventricular puncture to test the pressure. Three patients underwent endoscopic third ventriculostomy (ETV), the outcome of the patients was observed.Results:The pressure of subarachnoid was not equal to intraventricular, and the pressure of intraventricular was negative. Cisternography showed cerebrospinal fluid circulation obstruction in all 5 cases. The symptoms of 1 patient were improved after external negative pressure drainage, 3 patients were improved after further ETV and 1 patient had pulmonary infection without further surgical treatment.Conclusion:With the obstruction of cerebrospinal fluid circulation, the pressure of lateral ventricle and subarachnoid is different, when the pressure of brain or subarachnoid drop, the ventricular expansion under the effect of pressure gradient, intraventricular pressure drop even for the negative pressure. CT cisternography provides strong evidence for the diagnosis of this disease. External ventricular drainage with negative pressure and ETV are effective treatment methods.
