Research progress on the relationship between bilirubin and polycystic ovary syndrome
10.3760/cma.j.cn101721-20221023-000488
- VernacularTitle:胆红素与多囊卵巢综合征相关性的研究进展
- Author:
Mengdan SHEN
1
;
Junping HU
;
Mingxia GAO
Author Information
1. 兰州大学第一医院生殖医学中心，兰州 730000
- Keywords:
Polycystic ovary syndrome;
Bilirubin;
Insulin resistance;
Inflammation;
Oxidative stress
- From:
Clinical Medicine of China
2023;39(2):157-160
- CountryChina
- Language:Chinese
-
Abstract:
Polycystic ovary syndrome (PCOS) is a common reproductive endocrine and metabolic disease, and its pathogenesis is closely related to inflammation, insulin resistance, and metabolic disorders. Bilirubin is the final product of the destruction and degradation of senescent red blood cells in the body. In addition, bilirubin can be not only used to evaluate liver function damage and cytotoxicity, but also can anti-inflammatory, antioxidant, alleviate metabolic disorders, etc. Recently, studies have found a certain correlation between low levels of bilirubin and PCOS: the level of bilirubin in patients with PCOS is low, and the anti-inflammatory and antioxidant properties of bilirubin may play a protective role in the pathogenesis of PCOS.
