The relationship between shear wave elastography and pathological classification in nephrotic syndrome
10.3760/cma.j.cn431274-20230620-00884
- VernacularTitle:肾病综合征剪切波弹性成像与病理分型的关系
- Author:
Yingchen LUO
1
;
Chaomei WEN
;
Linqian PENG
;
Yajuan LI
;
Yanfeng YAO
Author Information
1. 重庆医科大学附属永川医院超声医学科，重庆 402160
- Keywords:
Nephrotic syndrome;
Elasticity imaging techniques;
Ultrasonography
- From:
Journal of Chinese Physician
2023;25(8):1144-1146,1152
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the clinical value of shear wave elastography in the diagnosis and pathological classification of nephrotic syndrome.Methods:A retrospective analysis was conducted on the clinical data of 43 patients with primary nephrotic syndrome (primary nephrotic syndrome group) diagnosed through renal biopsy at the Yongchuan Hospital Affiliated to Chongqing Medical University from June 2022 to March 2023. They were further divided into three subgroups: mesangial proliferative glomerulonephritis group, membranous nephropathy group, and minimal change nephropathy group. Another 30 healthy individuals were selected as the control group. We applied shear wave elastography to measure the shear wave velocity of the right renal lower pole parenchyma and statistically analyzed the differences in shear wave velocity between each group.Results:There was a statistically significant difference in shear wave velocity between the primary nephrotic syndrome group [(1.76±0.41)m/s] and the control group [(1.55±0.34)m/s] ( P<0.05); The shear wave velocity in the membranous nephropathy group [(1.97±0.36)m/s] was the highest, and there was a statistically significant difference ( P<0.05) compared to the small lesion nephropathy group [(1.54±0.42)m/s]; There was no statistically significant difference in shear wave velocity between the membranous nephropathy group and the mesangial proliferative glomerulonephritis group [(1.74±0.38)m/s], as well as between the mesangial proliferative glomerulonephritis group and the small lesion nephropathy group (all P>0.05). Conclusions:Shear wave elastography is a non-invasive examination that provides valuable clinical clues for the diagnosis and pathological classification of nephrotic syndrome by detecting the shear wave velocity of the kidney.
