Research progress in the regulation of exosomes on cell Ferroptosis
10.3760/cma.j.cn431274-20220927-00973
- VernacularTitle:外泌体对细胞铁死亡调控的研究进展
- Author:
Sheng ZHAO
1
;
Guodong WANG
;
Jiawen JIANG
;
Zhaofeng SUN
;
Chuanxing ZHAI
;
Yuanmin ZHANG
Author Information
1. 济宁医学院临床医学院，济宁 272067
- Keywords:
Exosomes;
Ferroptosis;
Lipid peroxidation;
Neoplasms
- From:
Journal of Chinese Physician
2023;25(7):1105-1109
- CountryChina
- Language:Chinese
-
Abstract:
Ferroptosis is an iron-dependent, apoptotic cell death caused by massive lipid peroxidation-mediated cell membrane damage. Recent evidence suggests that exosomes, as a 30-100 nm diameter follicular body, contain a variety of active ingredients such as proteins, various RNAs and lipids that can have a great impact on the diagnosis and treatment of related diseases by regulating cellular iron death. To this end, this paper elaborates the research significance of exosomes in the regulation of cell ferroptosis, analyzes their role in disease treatment, and reviews the relevant reports and studies on exosomes regulating cell ferroptosis in recent years.
