A case of nasopharyngeal carcinoma with autonomic nervous dysfunction and literature review
10.3760/cma.j.cn431274-20220721-00712
- VernacularTitle:以自主神经功能障碍为突出表现的鼻咽癌一例并文献复习
- Author:
Rui CHEN
1
;
Shuying LI
;
Weiting TANG
;
Jingwei WU
;
Yong YOU
Author Information
1. 海南医学院第二附属医院神经内科，海口 570100
- Keywords:
Nasopharyngeal carcinoma;
Autonomic dysfunction;
Syncope;
Paraneoplastic neuropathy;
Cranial nerve injuries
- From:
Journal of Chinese Physician
2023;25(5):685-690
- CountryChina
- Language:Chinese
-
Abstract:
Objective:A case of advanced nasopharyngeal carcinoma with autonomic dysfunction was reported and its pathophysiological mechanism was discussed.Methods:The diagnosis and treatment of a nasopharyngeal carcinoma patient with autonomic nervous dysfunction such as paroxysmal syncope was summarized, and the pathophysiological mechanism of this case was analyzed by searching related literature.Results:Nasopharyngeal carcinoma characterized by autonomic dysfunction was rare and had a poor prognosis. Autonomic dysfunction caused by nasopharyngeal carcinoma was associated with carotid sinus syndrome, parapharyngeal space syncope syndrome, glossopharyngeal nerve reflex and paraneoplastic neuropathy.Conclusions:Early detection and treatment is a key factor affecting the prognosis of nasopharyngeal carcinoma. Clinicians should consider nasopharyngeal carcinoma as one of the differential diagnoses in the diagnosis and treatment of patients with autonomic nervous dysfunction combined with cranial nerve damage.
