Current status and future of new technologies in the treatment of type 1 diabetes
10.3760/cma.j.cn431274-20230215-00159
- VernacularTitle:1型糖尿病治疗新技术的现状与未来
- Author:
Shuoming LUO
1
;
Zhiguang ZHOU
Author Information
1. 中南大学湘雅二医院代谢内分泌科,糖尿病免疫学教育部重点实验室,国家代谢性疾病临床医学研究中心,长沙 410011
- Keywords:
Diabetes mellitus, type 1;
Insulin;
Immunotherapy;
Cell therapy;
Islets of langerhans transplantation
- From:
Journal of Chinese Physician
2023;25(3):321-324
- CountryChina
- Language:Chinese
-
Abstract:
Type 1 diabetes mellitus (T1DM) is an organ-specific disease characterized by autoimmune damage to pancreatic β cells. Insulin therapy is the most basic and important treatment for T1DM, but insulin therapy cannot fundamentally terminate or improve the main cause of T1DM, namely the disorder of the immune regulation mechanism. With the advancement of science and technology, the continuous development of new insulin and hypoglycemic drugs has provided better means for glycemic control. Pancreas transplantation, islet transplantation, immunotherapy, and cell therapy have provided hope for the prevention or reversal of T1DM. It is of great significance to understand the current situation and future of new technologies for T1DM treatment for the research and management of T1DM patients.