Analysis of changes in cardiac structure and function in 363 patients with maintenance hemodialysis
10.3760/cma.j.cn431274-20220714-00675
- VernacularTitle:363例维持性血液透析患者心脏结构及功能改变特点分析
- Author:
Ying LEI
1
;
Bixian ZHONG
;
Qi WANG
;
Yanyan SU
;
Yunfang ZHANG
;
Dewang ZENG
Author Information
1. 广州市花都区人民医院，南方医科大学附属花都医院肾病学科，广州 510800
- Keywords:
Hemodialysis;
Echocardiography;
Hypertrophy, left ventricular;
Heart valve diseases
- From:
Journal of Chinese Physician
2023;25(2):216-219
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the characteristics of cardiac structure and function changes in maintenance hemodialysis (MHD) patients.Methods:The information of 363 MHD patients with dialysis age ≥3 months who were registered in Huadu District People′s Hospital of Guangzhou City before January 2020 was collected, and the echocardiographic screening was performed to analyze the changes in cardiac structure and function.Results:The most common abnormal changes of heart structure and function in MHD patients were valve regentation (69.7%), left ventricular hypertrophy (LVH) (51.8%), left ventricular diastolic dysfunction (29.8%), valve calcification (11.6%), and left ventricular systolic dysfunction (10.2%). With the increase of age, the left ventricular ejection fraction of MHD patients decreased, and the proportion of left ventricular diastolic dysfunction, left atrial enlargement and pulmonary hypertension increased (all P<0.05). Among 363 MHD patients, 188(51.8%) had LVH. It was found that LVH patients had higher average single ultrafiltration volume, higher brain natriuretic peptide (BNP) level, more type 2 diabetes, lower left ventricular ejection fraction (all P<0.05), and were more prone to chest tightness, chest pain, post activity shortness of breath, heart failure and other symptoms compared with the non-LVH patients (all P<0.05). Conclusions:Most MHD patients have different degrees of cardiac structural changes. Early intervention, reduction of single ultrafiltration volume and control of blood glucose are beneficial to improve the dialysis quality of MHD patients and reduce the occurrence of cardiovascular events.
