Research progress of transneuronal retrograde degeneration of retinal ganglion cells secondary to occipital lobe injury

VernacularTitle:枕叶损伤继发视网膜神经节细胞跨神经元逆行变性的研究进展
Author: Maomei SONG ¹ ; Suiyi XU ; Changxin LI
Author Information

1. 山西医科大学第一医院神经内科，太原　030001
Keywords: Occipital lobe injury; Retinal ganglion cells; Retrograde degeneration
From: Journal of Chinese Physician 2023;25(1):153-156
CountryChina
Language:Chinese
Abstract: In addition to visual field defects, occipital lobe injury can also cause fundus changes, such as retinal nerve fiber layer atrophy, ganglion cell complex atrophy and even optic nerve atrophy, and these fundus changes have a good correlation with the visual field defect site. It is considered to be caused by transneuronal retrograde degeneration (TRD) of retinal ganglion cells secondary to occipital lobe injury. These changes can be detected by means of optical coherence tomography, fundus examination, magnetic resonance imaging, etc. Among them, optical coherence tomography is more sensitive than other examinations. Here, the anatomical basis of TRD, case reports, pathogenesis, auxiliary examination, treatment and prognosis of TRD secondary to occipital lobe injury are reviewd.