The role of DDX5 RNA helicases on cancer progression and development
10.3760/cma.j.cn431274-20220429-00401
- VernacularTitle:DDX5在恶性肿瘤中作用机制的研究进展
- Author:
Guoqi LIU
1
;
Yumei HUANG
;
Jiaojiao SONG
;
Wenlong WANG
;
Xiangrui MA
;
Chenglong YU
;
Jinhua ZUO
Author Information
1. 滨州医学院附属医院口腔颌面外科，滨州 256699
- Keywords:
Neoplasms;
DEAD box protein 5;
DEAD-box RNA helicases
- From:
Journal of Chinese Physician
2022;24(12):1909-1912
- CountryChina
- Language:Chinese
-
Abstract:
DDX5 helicase (DEAD box helicases 5), also known as P68, is an important member of an ATP dependent RNA helicase.Studies have shown that DDX5 is abnormally expressed in a variety of cancers, targeting a variety of tumor related signal pathways, regulating upstream and downstream factors to affect the occurrence, invasion and migration of tumor cells. This article describes the biological role of DDX5 in malignant tumors and provides prospects for targeted treatment of tumors.
