Research progress on the relationship between exosomes and pain
10.3760/cma.j.cn431274-20220418-00355
- VernacularTitle:外泌体与疼痛关系的研究进展
- Author:
Long YUAN
1
;
Sen LI
;
Wanxiang LI
;
Jichao BIAN
;
Guodong WANG
Author Information
1. 济宁医学院临床医学院,济宁 272000
- Keywords:
Exosomes;
Neuropathic pain;
Inflammatory pain
- From:
Journal of Chinese Physician
2022;24(12):1901-1904
- CountryChina
- Language:Chinese
-
Abstract:
Exosomes are extracellular microbubbles related to intercellular communication, which have the ability to transport and transfer biological macromolecules. Pain will lead to a sharp decline in the quality of life of patients, and will give patients and society a heavy medical burden. More and more evidences show that the exosomes plays an important role in the pathological process of pain related diseases.Summarizing the exosomes and the biomolecules carried by them under different pain conditions, and identifying the specific exosomes related to the pain state will be helpful for early diagnosis and treatment of pain related diseases. In addition, the ability of exosomes to transmit information and its widespread characteristics in the body indicate that they have broad prospects as a new diagnosis and treatment tool in the field of pain. A better understanding of the relationship between the exosomes and pain will provide a novel and promising treatment for patients with pain.