Application value of humidifying high-flow nasal cannula oxygen therapy after weaning of pediatric intensive care unit patients
10.3760/cma.j.cn431274-20220426-00392
- VernacularTitle:加温湿化高流量鼻导管吸氧在PICU患儿撤机后的应用价值
- Author:
Junli LIU
1
;
Guiying WU
;
Xiaomeng GENG
;
Xinli YANG
;
Miaomiao ZHAO
;
Baohai SHI
Author Information
1. 泰安市中心医院（青岛大学附属泰安市中心医院、泰山医养中心）儿童内科，泰安 271000
- Keywords:
Intensive care units, pediatric;
Continuous positive airway pressure;
Noninvasive ventilation;
Ventilator weaning
- From:
Journal of Chinese Physician
2022;24(12):1842-1846
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the application value of humidifying high-flow nasal cannula oxygen therapy (HHFNC) in children with pediatric intensive care unit (PICU) after weaning.Methods:From January 2018 to October 2021, 42 children with endotracheal intubation admitted to PICU of Tai′an city Central Hospital were prospectively selected and randomly divided into HHFNC group and nasal continuous positive airway pressure (NCPAP) group, with 21 patients in each group. The blood gas analysis [arterial partial pressure of oxygen (PaO 2), partial pressure of carbon dioxide in artery (PaCO 2), PaO 2/oxygen concentration (FiO 2)], blood oxygen saturation (SaO 2), comfort, non-invasive ventilation time, and total hospital stay of the two groups of children 1 hour after using HHFNC and NCPAP were compared, and the rate of reintubation of trachea within 48 hours, gastroesophageal reflux, nasal injury, facial skin indentation, abdominal distension, and pulmonary air leakage were recorded. Results:There was no significant difference between the two groups in terms of blood gas analysis (PaO 2, PaCO 2, PaO 2/FiO 2), SaO 2, pulmonary air leakage, non-invasive ventilation time, hospital stay, and reintubation rate within 48 h after weaning (all P>0.05). Compared with NCPAP group, HHFNC group had higher comfort, lower incidence of facial skin indentation, gastroesophageal reflux, nasal injury and abdominal distension, and the difference was statistically significant (all P<0.05). Conclusions:HHFNC and NCPAP can both be used as the transitional respiratory support mode after weaning, and the clinical treatment effect are similar. The HHFNC group has higher comfort, which is more conducive to improving the tolerance of children, reducing adverse reactions, and has higher safety.
