Multimodal magnetic resonance imaging of subjective tinnitus related mood disorder
10.3760/cma.j.cn371468-20221108-00665
- VernacularTitle:主观性耳鸣情绪障碍的多模态磁共振成像
- Author:
Biao LI
1
;
Xiaomin XU
;
Yuchen CHEN
;
Jinghua HU
;
Jinjing XU
Author Information
1. 南京医科大学附属南京医院（南京市第一医院）耳鼻喉科，南京 210006
- Keywords:
Subjective tinnitus;
Mood disorders;
Neuroimaging;
Limbic system;
Default mode network
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2023;32(6):570-576
- CountryChina
- Language:Chinese
-
Abstract:
Subjective tinnitus refers to the subjective sound perception of patients in the absence of an external sound stimulus.Tinnitus patients are often accompanied by emotional disorders, such as depression and anxiety, which seriously affect the quality of life of patients.Therefore, understanding the mechanism underlying the occurrence of tinnitus emotional disorders can help relieve the pain of tinnitus.Tinnitus was considered a simple ear disease in the early stages, but with the progress of neuroimaging technology and the development of animal models, increasing attention has been given to the changes in the neural structure and function of tinnitus patients.As a powerful technique for in vivo investigation of neural activity in the brain, multimodal magnetic resonance has been widely used in the study of subjective tinnitus.By observing the changes of brain structure in subjective tinnitus patients, the neural mechanism of the occurrence and development of tinnitus has been explored.This article reviewed recent multimodal magnetic resonance imaging studies on the neuroimaging mechanisms of tinnitus with mood disorders, compared the differences in neural activity between subjective tinnitus patients and healthy people, and found that the limbic system, default mode network and other neural network abnormalities were closely related to the mood disorders of tinnitus.The application and development of multimodal magnetic resonance techniques in subjective tinnitus were also discussed to elucidate the neural mechanism of subjective tinnitus accompanied by mood disorders with the help of multimodal magnetic resonance techniques.
