Application of immunosuppressive agents in crtical coronavirus disease
10.3760/cma.j.cn121430-20221009-00901
- VernacularTitle:免疫抑制剂在危重型新型冠状病毒感染中的应用
- Author:
Zhicheng HE
1
;
Daiwei YANG
;
Tingxin WU
;
Lili LU
Author Information
1. 武汉科技大学医学院临床医学系，湖北武汉 430065
- Keywords:
SARS-CoV-2;
Cytokine storm;
Immunosuppressant;
Crtical coronavirus disease
- From:
Chinese Critical Care Medicine
2023;35(1):106-109
- CountryChina
- Language:Chinese
-
Abstract:
The outbreak of novel coronavirus (SARS-CoV-2) infection has brought great harm to people's life and social development. Although SARS-CoV-2 infection is more common in mild patients at present, considering the characteristics of crtical disease, rapid progress and high mortality, the treatment of critical patients are the focus of clinical attention. Immune imbalance which is characterized by cytokine storm plays a vital role in SARS-CoV-2 induced acute respiratory distress syndrome (ARDS), extrapulmonary multiple organ failure and even death. Therefore, the application of immunosuppressive agent in crtical coronavirus disease patients has a promising prospect. In this paper, different immunosuppressive agents and their application in crtical SARS-CoV-2 infection are reviewed, so as to provide reference for crtical coronavirus disease therapy.
