A Case of Refractory Variant Angina Relieved by Clonidine.
10.4070/kcj.1993.23.6.814
- Author:
Il Mun JEON
;
Soo Yeon WON
;
Jin Won JEONG
;
Yang Kyu PARK
;
Ock Kyu PARK
- Publication Type:Case Report
- Keywords:
Variant angina;
Coronary Spasm
- MeSH:
Calcium;
Clonidine*;
Humans;
Myocardial Ischemia;
Nitrates;
Spasm
- From:Korean Circulation Journal
1993;23(6):814-819
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Coronary spasm may be induced by a variety of physiologic and pharmacologic stimuli but specific receptor blockade has not been consistently shown to prevent the attacks. Most patients with variant angina respond well to treatment with calcium antagonists and nitrates. A small proportion of patients are refractory to this therapy. We report a case of the patient with a 9-year-history of variant angina who has been refractory to high doses of calcium antagonists and nitrates. The repeated addition of clonidine was consistently effective in abolishing both symptoms and objective evidence of myocardial ischemia in this particular patient.
