Research progress of mechanisms of oxidative stress in septic cardiomyopathy

VernacularTitle:氧化应激在脓毒性心肌病中作用机制的研究进展
Author: Shuai PENG ¹ ; Lihua ZHOU
Author Information

1. 内蒙古医科大学，呼和浩特　010110
Keywords: Oxidative stress; Septic cardiomyopathy; Mitochondria; Sepsis
From: Chinese Critical Care Medicine 2022;34(12):1337-1341
CountryChina
Language:Chinese
Abstract: Sepsis is currently defined as a life-threatening multiple organ dysfunction caused by host dysregulated response to infection, with high morbidity and mortality in intensive care units. Patients with sepsis are often complicated with cardiac dysfunction known as septic cardiomyopathy (SCM). The occurrence of SCM is related to the high mortality of patients, which has been closely concerned for a long time, and is also one of the challenges to be solved in the systematic treatment of sepsis. A large number of studies have shown that oxidative stress contributes to the pathogenesis of SCM. The role of oxidative stress in SCM and the potential treatment measures for redox imbalance are discussed in this paper.