Dead space fraction for treatment guidance and prognosis evaluation of acute respiratory distress syndrome
10.3760/cma.j.cn121430-20220601-00534
- VernacularTitle:死腔分数对急性呼吸窘迫综合征治疗指导及预后评价
- Author:
Siqing MA
1
;
Zhijian WANG
;
Litao GUO
Author Information
1. 青海省人民医院重症医学科,西宁 810007
- Keywords:
Dead space fraction;
Acute respiratory syndrome;
Mechanical ventilation;
Coronavirus disease 2019;
Prognosis
- From:
Chinese Critical Care Medicine
2022;34(12):1333-1336
- CountryChina
- Language:Chinese
-
Abstract:
Acute respiratory distress syndrome (ARDS) is a common cause of critical illness and high mortality from respiratory failure. Increased dead space fraction (VD/VT) was independently associated with lung injury and mortality of ARDS. VD/VT is readily obtained by bedside measurements of arterial blood gas and end-tidal carbon dioxide. Early attention and application of VD/VT as an indicator will help to better understand the pathophysiological of ARDS, guide clinical treatment, and better assess the severity and clinical prognosis of the disease.