The correlation between intestinal flora and glucose metabolism during pregnancy and the research progress on the application of probiotics
10.3760/cma.j.cn115822-20230405-00052
- VernacularTitle:肠道菌群与妊娠期糖代谢相关性及益生菌应用相关研究进展
- Author:
Yanbei DUO
1
;
Weigang ZHAO
Author Information
1. 中国医学科学院 北京协和医学院 北京协和医院内分泌科 国家卫生健康委员会内分泌重点实验室 100730
- Keywords:
Gestational diabetes mellitus;
Gut microbiota;
Metabolites;
Maternal and infant complications;
Probiotics
- From:
Chinese Journal of Clinical Nutrition
2023;31(3):186-192
- CountryChina
- Language:Chinese
-
Abstract:
Gut microbiota is the microbial community that resides on the surface of human intestinal mucosa. During normal pregnancy, the composition of gut microbiota may change dynamically with the progress of pregnancy. Gestational diabetes mellitus (GDM) is a common complication of pregnancy, which can affect maternal and neonatal intestinal flora, and affect the long-term glucose metabolism of mothers and infants through exacerbating insulin resistance and promoting inflammatory response. Adjustment of dietary structure and application of probiotics may regulate intestinal microbiota and improve maternal and neonatal glucose metabolism in GDM. Here we reviewed the correlation between intestinal flora and glucose metabolism during pregnancy, and discussed the effects of diet and probiotics on gut microbiota.
