Association analysis of various obesity-related indices and vitamin D deficiency in middle-aged and elderly population in Lanzhou
10.3760/cma.j.cn115822-20220610-00107
- VernacularTitle:兰州市中老年人群维生素D缺乏相关肥胖指标的比较分析
- Author:
Hang MIN
1
;
Fang YANG
;
Donghu ZHEN
;
Xulei TANG
;
Hongxia CHE
;
Conghui GUAN
;
Nan ZHAO
;
Lijuan LIU
;
Jie HAN
;
Yue YE
;
Mengran GUO
;
Xiaoshuang XU
Author Information
1. 兰州大学第一临床医学院内科学专业 730000
- Keywords:
Obesity;
Vitamin D deficiency;
Middle-aged and elderly population
- From:
Chinese Journal of Clinical Nutrition
2023;31(1):1-8
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze and compare the association between different obesity-related indices and vitamin D deficiency in middle-aged and elderly population dwelled in Lanzhou city.Methods:From May, 2011 to September, 2012, middle-aged and elderly individuals with complete baseline data were included via randomly cluster sampling from 3 communities in Lanzhou. The subjects were divided into 4 subgroups by vitamin D levels and various obesity-related indices were compared across subgroups with the same gender. The relationship between the obesity-related indices and the severity of vitamin D deficiency was analyzed using Spearman correlation analysis, and the effects of different obesity-related indices on the severity of vitamin D deficiency was analyzed using multivariate logistic regression analysis.Results:A total of 9 437 residents were included. The overall prevalence of vitamin D deficiency was 97.7%. Compared with the group with lower vitamin D level, participants in the group with higher vitamin D level showed evidently lower body mass index (BMI), waist circumference (WC), lipid accumulation product (LAP), visceral adiposity index (VAI) and triglyceride/ high density lipoprotein cholesterol (TG/HDL-C) ratio in the total population and females, while only WC, LAP, VAI and TG/HDL-C in the males (all P<0.05). Spearman correlation analysis showed that BMI, WC, LAP, VAI and TG/HDL-C were positively correlated with the severity of vitamin D deficiency in the total population and the females, while only LAP, VAI and TG/HDL-C in the males (all P<0.05) . Multivariate logistic regression analysis showed that higher levels of these obesity related indices were correlated with more severe vitamin D deficiency in the total population and the females, while only higher LAP, VAI and TG/HDL-C in the males (all P<0.05). The effects of higher LAP was the most prominant in the total population ,the females and the males. Conclusion:Various obesity phenotypes are closely related to vitamin D deficiency in middle-aged and elderly women, while only visceral obesity and abnormal lipid metabolism are related to vitamin D deficiency in middle-aged and elderly men, with LAP being the most important influencing factor.
