Research progress on enteral nutrition monotherapy and combination therapy in adults with Crohn's disease
10.3760/cma.j.cn115822-20220910-00191
- VernacularTitle:肠内营养及其联合治疗在成人克罗恩病患者中的研究进展
- Author:
Shuang LI
1
;
Fangmei LING
;
Junrong LI
;
Yidong CHEN
;
Mingyang XU
;
Liangru ZHU
Author Information
1. 华中科技大学同济医学院附属协和医院消化内科,武汉 430022
- Keywords:
Enteral nutrition;
Crohn's disease;
Adults;
Combination therapy
- From:
Chinese Journal of Clinical Nutrition
2022;30(6):340-345
- CountryChina
- Language:Chinese
-
Abstract:
Patients with Crohn's disease (CD) are often complicated with malnutrition and enteral nutrition is the preferred option for nutritional support. Enteral nutrition is the first-line therapy to induce remission of CD in children, but its application in adults has not been well established. In recent years, studies have found that enteral nutrition can not only improve the nutritional status in adult CD patients, but also induce and maintain CD remission through various mechanisms. Given its favorable nutritional efficacy and safety, enteral nutrition has been considered as the basic treatment for adult CD patients and often used in combination with other treatment approaches. However, any combination therapy should be assessed in terms of benefit and risk. This review aims to describe the efficacy and safety of enteral nutrition combined with other treatment approaches in adult CD patients and enumerate common applicable clinical settings, so as to better inform clinical treatment.