Effects of dezocine combined with sufentanil on continuous epidural analgesia after cesarean section
10.3760/cma.j.cn341190-20221026-00842
- VernacularTitle:地佐辛联合舒芬太尼在剖宫产术后持续硬膜外镇痛中的效果观察
- Author:
Jinhui GUO
1
;
Xingqiang GENG
;
Ye ZHANG
Author Information
1. 涡阳县中医院麻醉科，亳州 233600
- Keywords:
Cesarean section;
Analgesia,epidural;
Anesthesia and analgesia;
Analgesics;
Dezocine;
Sufentanil;
Pain measurement
- From:
Chinese Journal of Primary Medicine and Pharmacy
2023;30(7):1051-1055
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effects of dezocine combined with sufentanil on continuous epidural analgesia after cesarean section.Methods:Eighty-six pregnant women who were scheduled for cesarean section in Guoyang Hospital of Traditional Chinese Medicine from February to December 2021 were included in this randomized controlled study. These women were divided into an observation group and a control group ( n = 43/group). The women in the observation group underwent epidural analgesia with dizocine, sufentanil, and ropivacaine, while those in the control group underwent epidural analgesia with dizocine and ropivacaine. The visual analogue score, Ramsay sedation score, Bruggrmann comfort scale score, and the incidence of adverse reactions were compared between the two groups. Results:At 4, 8, 12, 24 hours after surgery, the visual analogue score (VAS) in the observation group was significantly lower than that in the control group ( t = 2.34, 5.89, 15.36, 16.23, all P < 0.05). At 4, 8, 12, and 24 hours after surgery, Ramsay sedation score in the observation group was significantly higher than that in the control group ( t = -6.31, -7.64, -7.49, -7.41, all P < 0.001). At 4, 8, 12, and 24 hours after surgery, Bruggrmann comfort scale score in the observation group was significantly higher than that in the control group ( t = -7.60, -10.40, -14.53, -13.80, all P < 0.001). There was a significant difference in the number of effective analgesic pump compressions between the observation and control groups [(3.00 ± 1.41) times vs. (7.23 ± 1.31) times, t = 14.42, P < 0.001]. No adverse reactions were observed in the observation group within 24 hours after surgery. Conclusion:Dezocine combined with sufentanil for epidural analgesia can effectively improve the analgesic effects after cesarean section and is highly safe.
