Curative effects of Shugan Hewei Zhitong Recipe on chronic gastritis complicated by Helicobacter pylori infection
10.3760/cma.j.cn341190-20211130-01326
- VernacularTitle:疏肝和胃止痛方治疗肝胃不和慢性胃炎伴幽门螺杆菌感染疗效观察
- Author:
Meihua LIU
1
;
Bei YANG
;
Ruofei HAO
;
Yu'an JIN
Author Information
1. 北京中医药大学附属护国寺中医医院中医内科，北京 100035
- Keywords:
Gastritis;
Helicobacter pylori;
Disharmony between liver and stomach;
Shugan hewei zhitong recipe;
Controlled clinical trial
- From:
Chinese Journal of Primary Medicine and Pharmacy
2023;30(5):646-650
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the curative effects of Shugan Hewei Zhitong Recipe on chronic gastritis complicated by Helicobacter pylori infection. Methods:Eighty-seven patients with chronic gastritis complicated by Helicobacter pylori infection who received treatment in the Huguosi Hospital of Traditional Chinese Medicine, Beijing University of Chinese Medicine, China from July 2018 to June 2020 were included in this study. They were randomly assigned to undergo treatment with either conventional Western medicine ( n = 43, control group) or Shugan Hewei Zhitong Recipe based on conventional Western medicine ( n = 44, observation group) for 2 weeks. Before and after treatment, traditional Chinese medicine syndrome scores were compared between the two groups. Curative effects of Shugan Hewei Zhitong Recipe on chronic gastritis complicated by Helicobacter pylori infection were evaluated. Results:Total response rate in the observation group was significantly higher than that in the control group [91% (40/44) vs. 72% (31/43), χ2 = 5.13, P = 0.024]. In each group, the traditional Chinese medicine symptom score post-treatment was significantly lower than the traditional Chinese medicine symptom score pre-treatment (both P < 0.001). After treatment, the traditional Chinese medicine score of the observation group was significantly lower than that of the control group ( P < 0.05). There were no adverse reactions in each group. Conclusion:Shugan Hewei Zhitong Recipe is safe and effective on chronic gastritis complicated by Helicobacter pylori infection, which is worthy of clinical promotion.
